Molecular subtypes of colorectal cancer in pre-clinical models show differential response to targeted therapies: Treatment implications beyond KRAS mutations.

Molecular subtypes of colorectal tumors are associated with prognosis and prediction for treatment benefit from chemotherapy.The purpose of this study was two-fold: 1) to determine the association of colorectal (CRC) molecular subtypes with response to targeted therapies in pre-clinical models and 2) to identify treatments for CRC stem-like subtype

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Isolation and characterization of microbial population associated with industrial waste effluent and their antibiotic sensitive pattern

Background: Both organic and inorganic chemicals are deposited in industrial effluents, which contain radioactive, metals, antibiotics, and carcinogenic substances.These effluents are directly or indirectly affecting the daily life of human.Through food chains, it migrates to human health and cased different diseases with different drug-resistant s

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The sub-fossil diatom distribution in the Beibu Gulf (northwest South China Sea) and related environmental interpretation

Located in northwestern South China Sea (SCS), the Beibu Gulf constitutes an environmentally sensitive region shaped by land-ocean-atmosphere Windsurf Board interactions in Asia between the western Pacific and eastern Indian Oceans.This study aims to provide a comprehensive view of the sub-fossil diatom biogeography, distribution pattern and oceano

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